The effect of transcutaneous electric nerve stimulation in patients with therapy-resistant hypertension

Objectives: Afferent nerve stimulation, such as acupuncture and transcutane ous electric nerve stimulation (TENS), has shown a blood pressure reduction in both animal and man. In the present open and non-controlled study we in vestigated the effect on 24-h ambulatory blood pressure of low frequency TE NS in a group of hypertensive subjects who do not respond properly to pharm acological treatment. Method: Twelve patients were investigated. The patients were treated with T ENS at two acupoints on both forearms for 30 min twice daily during 4 weeks . 24-hour ambulatory blood pressure monitoring was recorded 1 week before, at start, at the end and finally 1 week after the TENS treatment. Results: The blood pressure did not change significantly during the run-in period. After 4 weeks of TENS, the mean systolic blood pressure decreased b y 6.3 mm Hg (P < 0.05) and the mean diastolic blood pressure decreased by 3 .7 mm Hg (P < 0.05), The blood pressure reduction remained unchanged 1 week after treatment. There was no change in mean heart rate. Conclusion: The present study suggests that continuous TENS may have additi onal blood pressure-lowering properties in hypertensive patients who do not respond properly to pharmacological treatment. The effect of TENS may also have a prolonged effect.