Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule

Authors
Duh, CY Wang, SK Chung, SG Chou, GC Dai, CF
Citation
Cy. Duh et al., Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule, J NAT PROD, 63(12), 2000, pp. 1634-1637
Citations number
8
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
12
Year of publication
2000
Pages
1634 - 1637
Database
ISI
SICI code
0163-3864(200012)63:12<1634:CCASFT>2.0.ZU;2-#
Abstract
Three new cytotoxic cembrenolide diterpenes, sarcocrassolide (1), crassolid e (2), and 13-acetoxysarcocrassolide (3); a known cytotoxic cembrenolide, d enticulatolide (4); and two cytotoxic steroids, (24S)-24-methylcholestane-3 beta ,5 alpha ,6 beta -triol (5) and 24 zeta -methylcholestane-3 beta ,5 a lpha ,6 beta ,25-tetraol-25-monoacetate (6), have been isolated from the Fo rmosan soft coral Sarcophyton crassocaule. The structures of compounds 1-6 were determined by 1D and 2D spectral analysis.