Access to pyrralo- and pyrido[1,2-a]indole derivatives by intramolecular nitrone cycloadditions. Effect of steric factors on the regioselective product formation
Em. Beccalli et al., Access to pyrralo- and pyrido[1,2-a]indole derivatives by intramolecular nitrone cycloadditions. Effect of steric factors on the regioselective product formation, J ORG CHEM, 65(26), 2000, pp. 8924-8932
On starting from N-allyl-substituted 2-indolecarbaldehydes and exploiting t
he intramolecular nitrone cycloaddition methodology, we synthesized a numbe
r of the title fused-ring indole derivatives in racemic as well as enantiop
ure form.