Effectiveness of beta-glucan collagen for treatment of partial-thickness burns in children

Background/Purpose: Seta glucan collagen matrix (BGC), which combines the c arbohydrate beta-glucan with collagen, has been used as a temporary coverag e for adult partial thickness burns with reported good results. Observed ad vantages of BGC coverage include reduction of pain, improved healing, and b etter scar appearance. Potentially even more important in children is the e limination of painful daily dressing changes to the burned epithelial surfa ce, as well as decreased fluid loss. This report details the authors' 2-yea r experience with BGC in a pediatric burn center. Methods: Retrospective chart review of 225 consecutive pediatric patients t reated at our institution between 1997 and 1999 identified 43 patients (19% ) with suspected partial thickness burns treated with BGC as the primary wo und dressing. BGC was applied to a debrided burn wound and secured with ste ri-strips, kerlix, and an ace wrap. After 24 hours, adherence of the BGC wa s confirmed and then left open to air. Results: The most common cause of burn injury was scald (61%), followed by flame (37%), and contact (2%). The average age of patients was 5.5 years (r ange, 6 weeks to 16 years) and mean percent total body surface area burned was 9.3% (1% to 35%). Thirty-four patients (79%) had the BGC remain intact while the wound healed underneath, with excellent cosmetic results, minimal analgesic requirements, and no need for repetitive dressing changes. Nine patients (21%) had the BGC removed before wound healing: 6 patients lost th e BGC because of progression of the burn to full thickness, 2 had BGC nonad herence over a joint, and 1 had an unexplained nonadherence. Conclusions: Partial-thickness burns in children can be effectively treated with BGC with good results, even in infants and toddlers. BGC markedly sim plifies wound care for the patient and family and seems to significantly de crease postinjury pain. J Pediatr Surg 36:113-118, Copyright (C) 2001 by W. B. Saunders Company.