M. Oishi et al., CEREBRAL BLOOD-FLOW AND CEREBROVASCULAR RESPONSE TO ACETAZOLAMIDE IN PATIENTS WITH CHRONIC-ALCOHOLISM, Journal of Neurology, Neurosurgery and Psychiatry, 63(1), 1997, pp. 100-102
Cerebral blood flow and cerebrovascular response to acetazolamide were
studied in 12 patients with chronic alcoholism and 12 age matched hea
lthy controls. Blood flows in the cerebral cortex, thalamus, and putam
en were significantly lower in the chronic alcoholic group than in the
healthy control group. The increase in blood flow caused by acetazola
mide did not show any significant difference between the two groups. T
hese findings suggest that the decreased cerebral blood now in chronic
alcoholism is due to decreased cerebral metabolism.