Background - A study was undertaken to assess whether the therapeutic
aspects of published international asthma management guidelines are pr
actically applicable in developing countries. Methods - Questionnaires
were sent to expatriate doctors working in developing countries. Resu
lts - Forty one replies were received from 24 countries in Africa and
Asia. Oral salbutamol was prescribed ''usually'' or ''often'' by 35 of
the 41 respondents, theophyllines by 30, inhaled bronchodilators by 1
2, inhaled steroids by two, and cromoglycate by two. Theophyllines wer
e locally available in all 41 cases, oral salbutamol in 40, inhaled br
onchodilators in 34, and inhaled steroids (usually beclomethasone 50 m
u g) in only 15. Where they were available, the median (range) cost of
a beclomethasone 50 pg inhaler was 20% (6.8-100%) of average local mo
nthly income, salbutamol inhaler 13% (3.3-250%), 90 salbutamol 4 mg ta
blets 3.8% (0.8-75%), and 90 aminophylline 100 mg tablets 4.5% (0.5-70
%). If they were available locally at a cheaper price, 34 (83%) respon
dents would prescribe more inhaled steroids and 37 (90%) would prescri
be more inhaled bronchodilators. Conclusions - Many asthma patients in
developing countries are not receiving adequate treatment because the
required drugs are not available in their area or are prohibitively e
xpensive.