A simple preparation of syn-NH-amide aldols and amide-Baylis-Hillman adducts via a Michael-aldol tandem process

Authors
Kamimura, A Omata, Y Mitsudera, H Kakehi, A
Citation
A. Kamimura et al., A simple preparation of syn-NH-amide aldols and amide-Baylis-Hillman adducts via a Michael-aldol tandem process, J CHEM S P1, (24), 2000, pp. 4499-4504
Citations number
38
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
24
Year of publication
2000
Pages
4499 - 4504
Database
ISI
SICI code
1472-7781(2000):24<4499:ASPOSA>2.0.ZU;2-0
Abstract
The thiolate- or selenolate-induced Michael-aldol tandem process using seco ndary alpha,beta -unsaturated amides gave alpha -phenylthio- or alpha -phen ylseleno-methyl-beta -hydroxy amides syn-selectively, which were readily co nverted into NH-amide aldols or Baylis-Hillman adducts.