Linear-shaped motion of DNA in entangled polymer solutions under a steady field

We studied the electrophoretic behavior of DNA chains in linear-polymer sol utions using Brownian dynamics with an anisotropic friction tensor. We simu lated the linear-shaped motion of DNA observed in highly entangled solution s [Ueda et al.: Biophys. Chem. 71 (1998) 113] using a model with a chain se gment equal to 1/4 of the persistence length. A linear conformation is peen for a chain with high segment-density regions, which remain at the same po sitions in space, with a high anisotropy of friction, while a U-shaped conf ormation is seen for a chain with a low anisotropy of friction.