A five-year-old neutered male domestic shorthair cat was presented aft
er three episodes of urethral obstruction and anuria requiring relief
urethral catheterisation. A double contrast cystogram revealed the pre
sence of multiple small cystoliths which were radiolucent on plain rad
iographs. A perineal urethrostomy and a cystotomy were performed to re
lieve-the urethral obstruction and to remove the cystoliths. Quantitat
ive analysis revealed the cystoliths to be composed of 100 per cent xa
nthine. Clinical history suggested the xanthinuria to be naturally occ
urring. Unfortunately, the cat was killed in a road traffic accident t
wo months after the surgical procedure, preventing further long-term a
ssessment.