New catalytic synthetic methods in organic chemistry that satisfy increasin
gly stringent environmental constraints are in great demand by the pharmace
utical and chemical industries. In addition, novel catalytic procedures are
necessary to produce the emerging classes of organic compounds that are be
coming the targets of molecular and biomedical research. Enzyme-catalysed c
hemical transformations are now widely recognized as practical alternatives
to traditional (non-biological) organic synthesis, and as convenient solut
ions to certain intractable synthetic problems.