Asymmetric catalytic C-H activation applied to the synthesis of syn-aldol products

Authors
Davies, HML Antoulinakis, EG
Citation
Hml. Davies et Eg. Antoulinakis, Asymmetric catalytic C-H activation applied to the synthesis of syn-aldol products, ORG LETT, 2(26), 2000, pp. 4153-4156
Citations number
25
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
26
Year of publication
2000
Pages
4153 - 4156
Database
ISI
SICI code
1523-7060(200012)2:26<4153:ACCAAT>2.0.ZU;2-8
Abstract
[GRAPHICS] Rh-2(R-DOSP)(4)-catalyzed decomposition of methyl phenyldiazoacetate in the presence of tetraalkoxysilanes results in the asymmetric synthesis of syn- aldol products. This catalytic asymmetric intermolecular C-H activation pro ceeds by means of a rhodium-carbene-induced CH insertion.