One-month-old infant with multiple ulcers of stomach, small bowel, large bowel, and protein-losing enteropathy: Case report

Multiple inflammatory ulcers of the gastrointestinal tract are rare in youn g infants. Most cases are caused by infectious organisms, vasculitis, or an autoimmune process. We report a I-month-old infant who was healthy until h e presented with an inflammatory mesenteric cyst, and multiple ulcers of th e stomach, duodenum, jejunum, ileum, and colon. Histologically, the ulcerat ions were sharply demarcated, full thickness, and filled with macrophages. He had a low serum albumin and Ige due to protein-losing enteropathy. He wa s treated with supportive care and immunomodulating drugs. The gastrointest inal inflammation resolved by 3 and 1/2 years of age. The medications were withdrawn at 5 and 1/2 years of age he had no relapse of clinical symptoms. He continues to have asymptomatic mild hypoalbuminemia and low serum IgG. We could not find a report of a similar clinical presentation and outcome.