Mechanical occlusion of the patent ductus arteriosus with Jackson coils

The effectiveness and safety of a protocol for transcatheter patent ductus arteriosus (PDA) closure was assessed. Our goal is complete mechanical occl usion of the PDA in the catheterization laboratory by adding coils until it is no longer possible to cross the PDA with a guidewire. Detachable coil c losure of a PDA with a narrowest diameter of 2.4 +/- 0.1 mm was attempted i n 83 patients with a median age of 2.8 years (0.7 to 27.8 years) and whose median weight was 14.5 kg (6 to 61.6 kg). Coils were successfully implanted in 82 of 83 patients, and in 1 patient a large Rashkind double umbrella wa s used instead. Complete closure was obtained in 80 (97.6%) patients, 48 of those (59%) received more than one coil. Reintervention for residual shunt ing was required in only 1 patient and another patient has a trivial residu al shunt. Device embolization occurred in three cases. Despite the use of m ultiple coils there was no evidence of significant left pulmonary artery st enosis. The fluoroscopy time increased from 14.0 +/- 2.0 minutes for a sing le coil to 25.3 +/- 2.9 minutes for multiple coils (p < 0.01). Attempting t o obtain complete mechanical occlusion of the PDA during the implant proced ure by adding extra coils reduces the need for reintervention for residual or recurrent shunting.