The Hypocrealean epibiont of Baccharis coridifolia has been shown to synthe
size de novo a series of macrocyclic trichothecene antibiotics, such as ror
idin A, roridin E, verrucarin A and verrucarin J. The structures of the com
pounds were determined by spectroscopic methods (H-1- and C-13-NMR and FABM
S).