Isolation of taxoids from cell suspension cultures of Taxus wallichiana

Authors
Agrawal, S Banerjee, S Chattopadhyay, SK Kulshrestha, M Madhusudanan, KP Mehta, VK Kumar, S
Citation
S. Agrawal et al., Isolation of taxoids from cell suspension cultures of Taxus wallichiana, PLANTA MED, 66(8), 2000, pp. 773-775
Citations number
17
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
66
Issue
8
Year of publication
2000
Pages
773 - 775
Database
ISI
SICI code
0032-0943(200012)66:8<773:IOTFCS>2.0.ZU;2-X
Abstract
Cell suspension cultures of stem-derived callus of Taxus wallichiana in MS- F culture media were found to produce three C-14 oxygenated taxoids and one regular taxoid. The taxoids were identified as yunnanxane (1), 2 alpha ,5 alpha ,10 beta ,14 beta -tetraacetory-4(20),11-taxadiene (2), 2 alpha ,5 al pha ,10 beta -triacetoxy-14 beta-(2-methyl)-butyryloxy-4(20),11-taxadiene ( 3) and 1 beta -hydroxybaccatin I (4).