Sesquiterpenes from the Leaves of Ligularia fischeri var. spiciformis

Citation
Hj. Park et al., Sesquiterpenes from the Leaves of Ligularia fischeri var. spiciformis, PLANTA MED, 66(8), 2000, pp. 783-784
Citations number
14
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
66
Issue
8
Year of publication
2000
Pages
783 - 784
Database
ISI
SICI code
0032-0943(200012)66:8<783:SFTLOL>2.0.ZU;2-1
Abstract
From the leaves of Ligularia fischeri var. spiciformis, a new eremophilanol ide, 8 alpha -methoxy-6-oxoeremophil-7(11)-en-12,8-olide (6-oxoeremophileno lide) and a eudesmane-type sesquiterpene, (+)-intermedeol were isolated. Th e structures were determined on the basis of 2D-NMR spectral data. Data on cytotoxicity showed that the latter was clearly more potent than the former compound.