The authors report the successful repair of large lower abdominal hernia de
fects after transverse rectus abdominis muscle (TRAM) flap breast reconstru
ction in 11 patients using a technique of intraperitoneal application of sy
nthetic polypropylene (Prolene) mesh anchored to the peritoneal surface of
the abdominal wall tissues. Five of these patients had previously failed he
rnia repairs after a unipedicle TRAM flap breast reconstruction employing t
he onlay mesh technique, with two of the patients having undergone three pr
evious hernia repairs. The other six patients had developed large hernias a
fter bipedicle TRAM flap reconstruction without previous mesh supplementati
on of the abdominal wall repair. After their successful hernia repairs, all
of the patients healed without difficulty and demonstrated no sign of recu
rrence in an 8 to 36-month follow-up. Each patient returned to her activity
level before breast reconstruction.