A NATURAL EXPERIMENT ON THE EFFECTS OF OVARIAN HORMONES ON CARDIOVASCULAR RISK-FACTORS AND STRESS REACTIVITY - BILATERAL SALPINGO OOPHORECTOMY VERSUS HYSTERECTOMY ONLY

Citation
Cm. Stoney et al., A NATURAL EXPERIMENT ON THE EFFECTS OF OVARIAN HORMONES ON CARDIOVASCULAR RISK-FACTORS AND STRESS REACTIVITY - BILATERAL SALPINGO OOPHORECTOMY VERSUS HYSTERECTOMY ONLY, Health psychology, 16(4), 1997, pp. 349-358
Citations number
49
Categorie Soggetti
Psycology, Clinical
Journal title
ISSN journal
02786133
Volume
16
Issue
4
Year of publication
1997
Pages
349 - 358
Database
ISI
SICI code
0278-6133(1997)16:4<349:ANEOTE>2.0.ZU;2-#
Abstract
To test the effects of declining ovarian hormone levels on cardiovascu lar risk factors, blood pressure, lipids, weight, and physiological re sponses to stress were evaluated in 29 middle-aged premenopausal women prior to and following elective hysterectomy and/or bilateral salping o oophorectomy (BSO). Prior to surgery, there were no group difference s in standard or putative risk factors, with the exceptions of body co mposition measures and total cholesterol level. After surgery, women w ho had undergone BSO(n = 10) had higher levels of atherogenic lipids a nd stress-induced lipids and tended to have higher circulating levels of epinephrine and stress-induced systolic and diastolic blood pressur e than women who had undergone hysterectomy only (n = 19). This study is consistent with the hypothesis that presence of ovarian hormones pl ays a key role in determining women's risk factor status.