Selective synthesis of unsymmetrical 3,4-disubstituted and 4-substituted 2(5H)-furanones

Authors
Rossi, R Bellina, F Raugei, E
Citation
R. Rossi et al., Selective synthesis of unsymmetrical 3,4-disubstituted and 4-substituted 2(5H)-furanones, SYNLETT, (12), 2000, pp. 1749-1752
Citations number
43
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
12
Year of publication
2000
Pages
1749 - 1752
Database
ISI
SICI code
0936-5214(200012):12<1749:SSOU3A>2.0.ZU;2-I
Abstract
Easily available 3,4-dibromo-2(5H)-furanone undergoes regioselective pallad ium-catalyzed reaction with aryl(trialkyl)stannanes to give the correspondi ng 4-aryl-3-bromo-2(5H)-furanones in satisfactory yields. These monobromo d erivatives have proven to be useful precursors to unsymmetrical 3,4-diaryl- 2(5H)-furanones, 4-aryl-3-methyl-2(5H)-furanones and 4-aryl-2(5H)-furanones .