Nm. Maguire et al., CHEMOENZYMATIC SYNTHESIS AND SOME REACTIONS OF (13S)-HYDROXYOCTADECADIENOIC ACID [(13S)-HODE] AND ANALOGS, Journal of chemical research. Synopses, (10), 1994, pp. 376-377
Linoleic acid (2) and the corresponding alpha,beta-unsaturated acid (1
1) are transformed by soybean lipoxygenase to give (13S)-HODE (1) and
a mixture of trienes (13 and 14), of which one (13) was purified by a
two-step process; two macrocyclic lactones (5 and 7) were also prepare
d.