CHEMOENZYMATIC SYNTHESIS AND SOME REACTIONS OF (13S)-HYDROXYOCTADECADIENOIC ACID [(13S)-HODE] AND ANALOGS

Authors
MAGUIRE NM READ G RICHARDSON PF ROBERTS SM
Citation
Nm. Maguire et al., CHEMOENZYMATIC SYNTHESIS AND SOME REACTIONS OF (13S)-HYDROXYOCTADECADIENOIC ACID [(13S)-HODE] AND ANALOGS, Journal of chemical research. Synopses, (10), 1994, pp. 376-377
Citations number
16
Categorie Soggetti
Chemistry
Journal title
Journal of chemical research. Synopses → ACNP
ISSN journal
03082342
Issue
10
Year of publication
1994
Pages
376 - 377
Database
ISI
SICI code
0308-2342(1994):10<376:CSASRO>2.0.ZU;2-1
Abstract
Linoleic acid (2) and the corresponding alpha,beta-unsaturated acid (1 1) are transformed by soybean lipoxygenase to give (13S)-HODE (1) and a mixture of trienes (13 and 14), of which one (13) was purified by a two-step process; two macrocyclic lactones (5 and 7) were also prepare d.