Background Work-related asthma is a leading cause of occupational respirato
ry illness.
Methods Work-related asthma was studied in California over a 36-month perio
d, from March 1, 1993 to February 29, 1996. The surveillance system identif
ied cases from Doctor's First Reports (DFRs), a mandated physician reportin
g system. Structured follow-up telephone interviews of DFR asthma cases wer
e conducted to collect work history, exposure, and medical information. Sta
tewide employment data was used to calculate disease rates among industry g
roups.
Results Based on 945 cases of work-related asthma, the average annual repor
ting rate for work-related asthma in California was 25/million workers. We
estimate that the actual rare is 78/million, adjusted for likely underrepor
ting. Janitors and cleaners (625/million) and firefighters (300/million) ha
d the highest reporting rates of work-related asthma. Half of all work-rela
ted asthma cases were associated with agents not known to be allergens.
Conclusions A greater proportion of work-related asthma associated with irr
itant exposures was identified than has previously been reported. The surve
illance data provide a very conservative estimate of the incidence of work-
related asthma. Am. J. Ind. Med. 39:72-83, 2001. (C) 2001 Wiley-Liss, Inc.