Kaposi's sarcoma-like lesions and other nodules as cutaneous involvement in AIDS-related visceral leishmaniasis

A 40-year-old human immunodeficiency virus (HIV)-positive man had three rel apses of visceral leishmaniasis (VL). In the third he developed nodular ski n lesions of three types, some reminiscent of Kaposi's sarcoma, Biopsy of e ach type disclosed abundant dermal macrophages with a huge number of intrac ellular and extracellular Leishman-Donovan bodies, Rapid improvement of les ions was achieved after antiparasitic treatment, AIDS leads to atypical for ms of leishmaniasis, Leishmania has been detected both in normal and pathol ogical skin of these patients due to dissemination during VL, It is suspect ed that a considerable proportion of the population may be infected in ende mic areas, Leishmania being opportunistic, in immunosuppressed individuals. It is important to recognize the range of lesions that may occur in patien ts with HN and VL, many of which are non-specific and may cause diagnostic difficulty.