trans-Sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease

Authors
Buchovsky, AS Campetella, O Russomando, G Franco, L Oddone, R Candia, N Luquetti, A Cappa, SMG Leguizamon, MS
Citation
As. Buchovsky et al., trans-Sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease, CL DIAG LAB, 8(1), 2001, pp. 187-189
Citations number
12
Categorie Soggetti
Immunology
Journal title
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
ISSN journal
1071412X → ACNP
Volume
8
Issue
1
Year of publication
2001
Pages
187 - 189
Database
ISI
SICI code
1071-412X(200101)8:1<187:TIAAHS>2.0.ZU;2-V
Abstract
For the diagnosis of Chagas' disease, the trans-sialidase inhibition assay was able to resolve the results for samples with borderline results, to det ect as positive 60% of samples that were negative by conventional serology, and to discriminate idiopathic from chagasic megaviscera or cardiopathy, N o cross-reaction with sera from patients with other diseases was observed.