The multifaceted clinical syndrome of schizophrenia continues to unfold bef
ore the onset of psychosis, at onset and thereafter. We now know that the o
ccurrence of schizophrenia differs quite markedly between groups defined at
a social level, such as neighbourhoods, urban-rural dichotomies or ethnic
groups. This understanding of longitudinal phenotypes and of variation in i
ncidence is allowing research to explore interactions between individuals,
their genes, their immediate environments and their social contexts. Curr O
pin Psychiatry 14:39-43. (C) 2001 Lippincott Williams & Wilkins.