Linear atrophoderma of Moulin

We report a typical case of linear atrophoderma of Moulin that represents a distinct clinical entity. A 17-year-old woman presented with hyperpigmente d and atrophic band-like skin lesions measuring 3-5 cm in breadth on the ri ght side of her trunk and on the right buttock, in an arrangement following the system of Blaschko's lines. The skin lesions had a normal texture and showed no signs of inflammation, lilac ring, erythema, induration, sclerosi s or depigmentation. Routine laboratory data were normal. Antinuclear antib odies and anti-Scl70-antibodies were negative. Histopathologically, a moder ate diffuse hyperpigmentation within the lower epidermis, a focal vacuolar degeneration of the basal layer, and a few dermal perivascular lymphocytes accompanied by signs of pigment incontinence were noted. Intravenous penici llin G was administered for 14 days in a dosage of 10 x 10(6) IU twice dail y. This treatment was repeated after 3 and 9 months. No effect was noted. L inear atrophoderma of Moulin takes a chronic course without progression or regression. The disease leads to significant cosmetic impairment and this m ay cause emotional stress. Due to its relationship to idiopathic atrophoder ma of Pierini-Pasini and linear scleroderma, treatment with intravenous pen icillin was tried. In our case it had no effect.