T. Becucci et al., 3-DEOXY-D-GLYCERO-PENTULOSE - A CONVENIENT STARTING MATERIAL FOR THE SYNTHESIS OF 4-HYDROXYPROLINOL, Gazzetta chimica italiana, 127(2), 1997, pp. 73-78
3-deoxy-D-glycero-pentulose, 1, is an uncommon keto sugar which was sh
own to be an useful starting material for the synthesis of the mono-su
bstituted prolinol 2. The simple reactions selected and optimised to t
ransform 1 into 2, make the new synthetic approach an interesting alte
rnative to the already described methods for the proline ring formatio
n.