Cannabis and tobacco: cofactors favoring juvenile obstruent arteriopathy.

The causal effect of cannabis, associated or not with smoking, in juvenile thromgoangeitis disorders such as Leo Buerger disease, has been suggested. We describe here a case of a 30-year-old woman who smoked cannabis and deve loped intermittent claudication of the lower limbs. Female sex and proximal localization of the lesions (external iliac artery) are not usually descri bed in "cannabis arteritis". Cannabis would be involved no only in the path ogenesis of juvenile obstruent arteriopathy, but also in the development of atheromatous lesions in the young subject.