Effect of Isoflupredone acetate (Predef. 2X) on ovulation and oestrous cycle in mare

To evaluate the effect of Isoflupredone acetate (Predef. 2x) oil ovulation and the length of the oestrus cycle in the mare, six non-pregnant reproduct ively sound mix breed mares were used ill, this study, The first oestrus cy cles of the mares were monitored and considered as control oestrus cycles. Oestrus cycles of the mares were synchronized using a dose of prostaglandin F2 alpha (Lutalyse, 10 mg/mare) and hCG (3000 I.U./mare). Each, mare was i njected intramuscularly 20 mg of Isoflupredone acetate from day 10 of the o estrous cycle up to the day of ovulation. Ovulation occured ill, all mares 24 to 48h after hCG treatment. There was no significant difference in the L ength of the oestrus cycle, the duration of the follicular and luteal phase s between the control and Isoflupredone acetate treated oestrus cycles. It is concluded that there was Ilo detrimental effect of Isoflupredone acetate olt the length of oestrus cycle and ovulation in the mare.