Bilateral transient hearing loss associated with vincristine therapy: Casereport

Authors
Aydogdu, I Ozturan, O Kuku, I Kaya, E Sevinc, A Yildiz, R
Citation
I. Aydogdu et al., Bilateral transient hearing loss associated with vincristine therapy: Casereport, J CHEMOTHER, 12(6), 2000, pp. 530-532
Citations number
9
Categorie Soggetti
Pharmacology
Journal title
JOURNAL OF CHEMOTHERAPY
ISSN journal
1120009X → ACNP
Volume
12
Issue
6
Year of publication
2000
Pages
530 - 532
Database
ISI
SICI code
1120-009X(200012)12:6<530:BTHLAW>2.0.ZU;2-E
Abstract
Vincristine, adriamycin, and dexamethasone (VAD) chemotherapy protocol is f irst-choice treatment in newly diagnosed multiple myeloma patients in many centers. Sudden hearing loss associated with vincristine therapy is a rarel y observed event in the VAD protocol. We describe a 69-year old male patien t diagnosed with multiple myeloma 7 months ago who developed sudden bilater al hearing loss related to vincristine therapy. This uncommon adverse effec t of vincristine is discussed and the literature reviewed.