Calcium intake and body weight

Citation
Km. Davies et al., Calcium intake and body weight, J CLIN END, 85(12), 2000, pp. 4635-4638
Citations number
19
Categorie Soggetti
Endocrynology, Metabolism & Nutrition","Endocrinology, Nutrition & Metabolism
Journal title
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
ISSN journal
0021972X → ACNP
Volume
85
Issue
12
Year of publication
2000
Pages
4635 - 4638
Database
ISI
SICI code
0021-972X(200012)85:12<4635:CIABW>2.0.ZU;2-P
Abstract
Five clinical studies of calcium intake, designed with a primary skeletal e nd point, were reevaluated to explore associations between calcium intake a nd body weight. All subjects were women, clustered in three main age groups : 3rd, 5th, and 8th decades. Total sample size was 780. Four of the studies were observational; two were cross-sectional, in which body mass index was regressed against entry level calcium intake; and two were longitudinal, i n which change in weight over time was regressed against calcium intake. On e study was a double-blind, placebo-controlled, randomized trial of calcium supplementation, in which change in weight during the course of study was evaluated as a function of treatment status. Significant negative associati ons between calcium intake and weight were found for all three age groups, and the odds ratio for being overweight (body mass index, >26) was 2.25 for young women in the lower half of the calcium intakes of their respective s tudy groups (P < 0.02). Relative to placebo, the calcium-treated subjects i n the controlled trial exhibited a significant weight loss across nearly 4 yr of observation. Estimates of the relationship indicate that a 1000-mg ca lcium intake difference is associated with an 8-kg difference in mean body weight and that calcium intake explains <similar to>3% of the variance in b ody weight.