PROGNOSTIC-SIGNIFICANCE OF FLOW-CYTOMETRY IN SQUAMOUS-CELL BRONCHOGENIC CANCER - RETROSPECTIVE STUDY OF 61 CASES

To assess the prognostic value of flow cytometric analysis, 61 cases o f operated squamous cell lung carcinoma were studied in terms of desox yribonucleic acid (DNA) nuclear content and percentage of cells in DNA synthesis phase (% S). These parameters were determined on a fresh su rgical sample. The S % was obtained in 25 cases. DNA index (DI) and % S were compared with survival and usual clinicopathologic characterist ics for the prediction of survival DNA content classified as DNA-diplo id and DNA-aneuploid is not a prognostic factor for survival. DI highe r than 2 seems to be predictive but needs confirmation. The % S and mu ltiploidy are not predictive factors for survival.