Effect of fluconazole on agar invasion by Candida albicans

Authors
Kontoyiannis, DP Tarrand, J Prince, R Samonis, G Rolston, KVR
Citation
Dp. Kontoyiannis et al., Effect of fluconazole on agar invasion by Candida albicans, J MED MICRO, 50(1), 2001, pp. 78-82
Citations number
10
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF MEDICAL MICROBIOLOGY
ISSN journal
00222615 → ACNP
Volume
50
Issue
1
Year of publication
2001
Pages
78 - 82
Database
ISI
SICI code
0022-2615(200101)50:1<78:EOFOAI>2.0.ZU;2-X
Abstract
Subinhibitory concentrations of azoles are known to inhibit hyphal branchin g of Candida albicans in liquid media. This study showed that subinhibitory concentrations of fluconazole also inhibit agar invasion by C. albicans in YPD solid medium. Agar invasion was markedly inhibited in two C. albicans strains that were resistant to fluconazole. This suggests that the degree t o which fluconazole inhibits agar invasion by C. albicans hyphae could serv e as a marker of susceptibility to azoles.