Neutrophilic dermatoses are characterized histologically by a sterile infil
tration of neutrophils throughout the dermis. The condition ma) affect vari
ous internal organs, notably the lungs, the digestive tract, and the joints
, whereas muscle impairment is considered to be extremely rare. We describe
the case of a patient with pyoderma gangrenosum in whom severe sterile neu
trophilic myositis developed as the first manifestation of an acute myeloge
nous leukemia.