Md. Holzman et al., Use of healthcare resources among medically and surgically treated patients with gastroesophageal reflux disease: A population-based study, J AM COLL S, 192(1), 2001, pp. 17-24
BACKGROUND: Gastroesophageal reflux disease (GERD) is a common disorder tha
t may be effectively managed medically or surgically. Direct evaluations of
medical resource use are needed to better understand the relative costs of
these alternatives. This study compared medical care use for a group of pa
tients receiving surgical treatment for GERD with that for a comparable gro
up of patients receiving medical management.
STUDY DESIGN: We conducted a retrospective matched cohort study of Tennesse
e Medicaid (TennCare) patients with GERD undergoing surgical treatment in 1
396 and a group of patients who received medical therapy during the same pe
riod. Administrative TennCare data provided computerized records that could
be used to identify patients and measure healthcare use. There were 7,502
people who met all of the conditions for inclusion in the study, including
at least two encounters with a diagnosis of GERD. One hundred thirty-five o
f these who underwent fundoplication constituted the surgically treated coh
ort. The 250 persons in the medically treated cohort were selected randomly
from the remaining nonsurgical patients and matched to the surgical cohort
by age, gender, race, managed care organization, and acid suppression drug
use in the baseline year. The principal outcome of interest was total use
of medical resources, including prescription medication.
RESULTS: The surgical and medical cohorts did not differ significantly by d
emographic characteristics or by baseline use of pharmaceuticals. During th
e baseline year the surgically treated patients were prescribed 302 (95% CI
: 270-334) days of GERD treatment and the matched medical patients were pre
scribed 292 (95% CI: 267-317) days of GERD treatment. Surgically treated pa
tients used more GERD-related outpatient resources (physician visits and di
agnostic testing) in the baseline year, particularly in the 3 months before
operation, when they had a mean of more than four outpatient encounter-day
s. In the followup year, use of GERD-related pharmaceuticals decreased mark
edly in the surgical cohort. These patients were prescribed an average of 1
23 days (95% CI: 94-153) of therapy, which was only 36% of that for medical
patients (339 days [95% CI: 308-370]). More than 29% of surgical patients
were prescribed no GERD-related drugs in the followup year compared with 6%
of the medically treated group. The mean number of inpatient days for the
fundoplication procedure was 3.2 (35% CI: 2.7-3.6), with a range of 0 to 13
days. There were no differences between the two groups in other healthcare
use.
CONCLUSIONS: Our results show that in a 1-year period of followup, surgical
treatment of severe gastroesophageal reflux disease led to a 64% postsurgi
cal reduction in GERD medication use, with no increase in use of other medi
cal services. (J Am Coll Surg 2001;192:17-24. (C) 2001 by the American Coll
ege of Surgeons).