Mitosis: a history of division

Mitosis has been studied since the early 1880s, to the extent that we now h ave a detailed, but still incomplete, description of spindle dynamics and m echanics, a sense of potential mechanochemical and regulatory mechanisms at a molecular level, and a long list of mitotic proteins. Here we present a personal view of how far we have come, and where we need to go to fully und erstand the mechanisms involved in mitosis.