Progress in cardiovascular biology: PPAR for the course

Authors
Lazar, MA
Citation
Ma. Lazar, Progress in cardiovascular biology: PPAR for the course, NAT MED, 7(1), 2001, pp. 23-24
Citations number
12
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
NATURE MEDICINE
ISSN journal
10788956 → ACNP
Volume
7
Issue
1
Year of publication
2001
Pages
23 - 24
Database
ISI
SICI code
1078-8956(200101)7:1<23:PICBPF>2.0.ZU;2-#
Abstract
Studies on mice lacking the peroxisome proliferator-activated receptor (PPA R) suggest that PPAR ligands reduce lipid accumulation in foamy macrophages , and may target other receptors. These findings warrant an in-depth invest igation into the gene regulatory mechanisms of PPAR ligands, which are curr ently being developed as drugs to treat atherosclerosis and diabetes.