A systematic method is described for the optimized design of quantum-well s
tructures, in respect to maximizing the stimulated gain in optically pumped
intersubband lasers. It relies on applying supersymmetric quantum mechanic
s to an initial Hamiltonian, in order to (i) add one bound state below the
spectral range of the initial Hamiltonian, and (ii) to generate a parameter
-controlled family of isospectral Hamiltonians with the desired energy spec
trum. By changing the value of the control parameter one changes the potent
ial shape and thus the values of dipole matrix elements and electron-phonon
scattering matrix elements. The use of this procedure is demonstrated by d
esigning an appropriate smooth or stepwise-constant graded AlxGa1-xAs terna
ry alloy quantum well.