Purpose: To compare the image quality of high-resolution (HR) spiral CT sca
ns from a multislice CT scanner with sequential HRCT scans from a singlesli
ce CT scanner. Materials and Methods: 20 patients with diffuse lung disease
received a high-resolution spiral CT on a multislice scanner (4 slices) an
d 5 HRCT single slices (1 mm) on a singleslice scanner. Scan parameters of
the multislice scanner were: Collimation 4 x 1 mm, pitch 6, slice thickness
1 mm. 5 HRCT slices were compared to the corresponding HR spiral CT slices
using a 5-point scale by 5 radiologists with regard to the image quality a
nd the number of artifacts. The evaluation was performed with a multivariat
e analysis (MANOVA test). Results: Overall impression of image quality, noi
se, central vessels and bronchi, and all pathological changes were not sign
ificantly different between the two CT methods. Sequential HRCT scans were
considered to be significantly better than HR spiral CT scans for spatial r
esolution (p=0.02), depiction of peripheral vessels (p=0.02), and of small
bronchi (p=0.05), and significantly worse for depiction of interlobar septa
(p<0.001). Diagnostically relevant differences were found in only 2.2%. Br
eathing and heartbeat artifacts each were 3 times higher in the sequential
HRCT technique than in the multislice-spiral technique (p<0.0001). Conclusi
on: HR spiral CT scans performed on a multislice CT scanner provide signifi
cantly less artifacts and an equal diagnostic image quality compared to seq
uential HRCT scans performed on a singleslice CT scanner. Multislice spiral
CT in HR technique may replace the common scanning technique with conventi
onal spiral CT and additional HRCT scans for diffuse lung diseases.