Reaction of diethyl phosphorisocyanatidite with 3,4-dichloro-5-hydroxy-2(5H)-furanone

Authors
Polezhaeva, NA Volodina, YM Sakhibullina, VG Loginova, IV Galkin, VI Cherkasov, RA
Citation
Na. Polezhaeva et al., Reaction of diethyl phosphorisocyanatidite with 3,4-dichloro-5-hydroxy-2(5H)-furanone, RUSS J G CH, 70(6), 2000, pp. 851-853
Citations number
8
Categorie Soggetti
Chemistry
Journal title
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
ISSN journal
10703632 → ACNP
Volume
70
Issue
6
Year of publication
2000
Pages
851 - 853
Database
ISI
SICI code
1070-3632(200006)70:6<851:RODPW3>2.0.ZU;2-S
Abstract
Reaction of diethyl phosphorisocyanatidite with 3,4-dichloro-5-hydroxy-2(5H )-furanone (mucochloric acid) is accomplished by mixing the reagents and le ads to a bicyclic phosphonamidate. The highly reactive isocyanato substitut ion at the sigma (3)-phosphorus atom permits one to effect cyclization afte r the first stage of the Arbuzov reaction and thus much extend the syntheti c potential of phosphorylation of mucochloric acid derivatives.