Chemistry and structure of diterpenes of the Kaurane series: II. Reductionof isosteviol

Authors
Al'fonsov, VA Bakaleinik, GA Gubaidullin, AT Kataev, VE Kovylyaeva, GI Konovalov, AI Litvinov, IA Strobykina, IY Strobykin, SI Andreeva, OV Korochkina, MG
Citation
Va. Al'Fonsov et al., Chemistry and structure of diterpenes of the Kaurane series: II. Reductionof isosteviol, RUSS J G CH, 70(6), 2000, pp. 953-960
Citations number
12
Categorie Soggetti
Chemistry
Journal title
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
ISSN journal
10703632 → ACNP
Volume
70
Issue
6
Year of publication
2000
Pages
953 - 960
Database
ISI
SICI code
1070-3632(200006)70:6<953:CASODO>2.0.ZU;2-Q
Abstract
Individual (4 alpha ,8 beta ,13 beta)-16-hydroxy-13-methyl-17-norkauran-18- oic acid was obtained by reduction with sodium borohydride of the tetracycl ic kauranoid isosteviol isolated from Stevia rebaudiana Bertoni. The struct ure of the acid was established by X-ray diffraction analysis. The reductio n of isosteviol was found to occur with a high stereocontrol.