Anaemia and thrombocytopenia of unexplained aetiology

Authors
Colombo, E Krause, M Moch, H
Citation
E. Colombo et al., Anaemia and thrombocytopenia of unexplained aetiology, SCHW MED WO, 130(51-52), 2000, pp. 2009-2016
Citations number
29
Categorie Soggetti
General & Internal Medicine
Journal title
SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT
ISSN journal
00367672 → ACNP
Volume
130
Issue
51-52
Year of publication
2000
Pages
2009 - 2016
Database
ISI
SICI code
0036-7672(200012)130:51-52<2009:AATOUA>2.0.ZU;2-V
Abstract
A 35-year-old male patient with long lasting HIV infection presented with c onfusion, haemolytic anaemia and thrombocytopenia. After a stable course ov er 7 days he suddenly developed coma and cardiogenic shock and died. Autops y revealed thrombotic thrombocytopenic purpura with fibrin-rich deposits in the microvasculature of the brain, heart and pancreas. The pathogenesis an d differential diagnosis of this fulminant disease are discussed.