We report on a patient who had giant cell tumor involving multiple bones of
the mid-foot. The tumor originated from the navicular bone, but also destr
oyed the cuboid, and all cuneiform bones. This unusual presentation of gian
t cell tumor presented a therapeutic challenge for the surgeons. The patien
t was treated with en bloc resection and the bony defect replaced with a ma
ssive iliac crest graft which united within 9 months and has remained stabl
e for 7 years without local recurrence, and with excellent function of the
foot.