Oxidative aryl coupling reactions: a biomimetic approach to configurationally unstable or axially chiral biaryl natural products and related bioactive compounds

Authors
Bringmann, G Tasler, S
Citation
G. Bringmann et S. Tasler, Oxidative aryl coupling reactions: a biomimetic approach to configurationally unstable or axially chiral biaryl natural products and related bioactive compounds, TETRAHEDRON, 57(2), 2001, pp. 331-343
Citations number
83
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
2
Year of publication
2001
Pages
331 - 343
Database
ISI
SICI code
0040-4020(20010107)57:2<331:OACRAB>2.0.ZU;2-9
Abstract
Phenolic and non-phenolic oxidative aryl coupling reactions were successful ly used in the efficient synthesis of diverse natural products and related compounds in the fields of biphenyls, biscarbazoles and bisnaphthylisoquino lines. For sterically more hindered biaryls, which consequently show the ph enomenon of axial chirality, the products were prepared in an atropisomeric ally pure form. Their absolute axial configurations were assigned mainly by experimental and computational CD investigations. (C) 2000 Elsevier Scienc e Ltd. All rights reserved.