SYNTHESIS OF A CHIRAL 1-BETA-METHYLCARBAPENEM KEY INTERMEDIATE USING RADICAL CYCLIZATION OF N-VINYLIC ALPHA-BROMO AMIDES

Authors
ISHIBASHI H KAMEOKA C KODAMA K KAWANAMI H HAMADA M IKEDA M
Citation
H. Ishibashi et al., SYNTHESIS OF A CHIRAL 1-BETA-METHYLCARBAPENEM KEY INTERMEDIATE USING RADICAL CYCLIZATION OF N-VINYLIC ALPHA-BROMO AMIDES, Tetrahedron, 53(28), 1997, pp. 9611-9622
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
28
Year of publication
1997
Pages
9611 - 9622
Database
ISI
SICI code
0040-4020(1997)53:28<9611:SOAC1K>2.0.ZU;2-S
Abstract
The chiral 1 beta-methylcarbapenem key intermediate 5 was synthesized by using radical cyclization of N-vinylic alpha-bromo amide 18 as a ke y step. (C) 1997 Elsevier Science Ltd.