We administered Pulsatilla miniplex(R) to twenty Holstein-Friesian cows 2 h
ours, 15, 25 and 35 days after delivery. All of them were clinically examin
ed on days 15, 25, 35 and 45 after term and subsequently inseminated. Each
cow, which failed to conceive after the third insemination, was classified
as not pregnant. Another group of twelve cows in the same farm served as co
ntrols. Uterine regression took shorter time in treated animals: on day 25
clinical uterine involution was completed in 75 % of the cows, compared wit
h 50 % in the control group. Treated cows showed better fertility results t
han controls: total pregnancy rate (75 vs. 58.3 %), pregnancy rate followin
g first insemination (53.8 vs. 28.6 %), insemination index (1.5 vs. 2.3) an
d the average interval between term and subsequent pregnancy (84.8 vs. 120.
1 days). The interval between parturition and time of first insemination, h
owever, was shorter in controls than in treated animals (55.7 vs. 68.2 days
). By treating the cows with Pulsatilla miniplex(R) we were able to shorten
postpartal uterine regression and to increase fertility - e.g. inseminatio
n index and interval between term and subsequent pregnancy - significantly.