In a recent survey of women with HIV, prayer was mentioned as a very import
ant source in decision making about HIV antiretroviral therapy. As a follow
-up to this finding, we conducted in-depth interviews with 51 women attendi
ng a comprehensive HIV care center to better understand the role of prayer
in their decisions about taking antiretroviral therapy. The sample consiste
d predominately of African American (80%) women with a median age of 31 yea
rs from St. Louis and surrounding areas. Forty-seven (92%) reported that pr
ayer was an important source for HIV medication decision making, with 30 (5
9%) considering prayer more important than the physician. Twenty-nine (57%)
perceived a qualitative difference between prayer and the physician, which
created a sense of conflict for some. Thirty (59%) wished that the physici
an knew more about the role of prayer in their lives. Our findings reveal c
ompelling issues: (a) the willingness of the women to talk about prayer as
a resource and its importance in HIV disease management, (b) the roles that
prayer and the physician play in HIV medication decision-making, and (c) w
ays prayer can be addressed in a medical setting.