Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-Indians

Authors
Miller, M Rhyne, J Khatta, M Parekh, H Zeller, K
Citation
M. Miller et al., Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-Indians, AM J CARD, 87(2), 2001, pp. 220
Citations number
9
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
87
Issue
2
Year of publication
2001
Database
ISI
SICI code
0002-9149(20010115)87:2<220:POTAPP>2.0.ZU;2-M
Abstract
Potential mechanisms accounting for the high cardiovascular death rates obs erved in Asian-Indians are dyslipidemia and insulin resistance. Polymorphis ms in the APOC3 promoter (-455 T/C and -482 C/T) were frequently encountere d in young Asian-Indians and they correlated with reduced concentrations of apolipoprotein A-I.