Because self reporting of substance use may not be reliable, physicians rel
y on drug screening. We tested the hypothesis that drug screening alone is
sufficient to detect substance use in ED psychiatric patients. We prospecti
vely evaluated patients receiving psychiatric consultation over 6 months en
ding in April 1998 in an urban medical/psychiatric ED with 42,000 annual vi
sits, After informed consent, patients underwent a structured interview by
trained research associates who queried regarding substance use in the past
3 days. This self report was compared with urine drug screen results for 1
1 substances of abuse. Standard descriptive statistical techniques were use
d. Kappa statistics were used to assess concordance between history and dru
g screens, Two hundred eighteen patients participated, 124 had a urine drug
screen obtained, Patients with and without urine drug screens were similar
with respect to age (34.9 Versus 34.9 years, P =.3) and psychiatric diagno
sis (P =.24). Overall, there was only fair concordance between history and
drug screens (kappa = 0.46). History alone detected substance use in 70 pat
ients (57%); drug screening alone detected substance use in 77 patients (62
%), The combination of history and drug screening more often detected subst
ance use than either alone (90 pts (73%); P <.05 for both comparisons), Dep
ending on the particular drug, there was wide variation in concordance betw
een history and drug screen (kappa's varied from 0.07 for ethanol to 0.79 f
or cocaine), History was better than drug screening for ethanol use (40 ver
sus 10 patients), and THC (28 versus 15 pts), Drug testing alone was never
significantly better than history, Although self-reporting of substance use
is not reliable, reliance on drug screening alone is also flawed. Optimal
identification of drug use in emergency department psychiatric patients req
uires both history and drug screening, (Am J Emerg Med 2001;19:49-51. Copyr
ight (C) 2001 by W.B. Saunders Company).