In the United States, 87.3% of the patients with end-stage renal disease (E
SRD) requiring dialysis are treated with hemodialysis (HD) and 12.7% with p
eritoneal dialysis (PD). This represents a greater use of HD than in many o
ther nations. We mailed a survey questionnaire to members of the National K
idney Foundation Council on Dialysis to better understand the attitudes of
American nephrologists toward dialysis modality decisions. We received resp
onses from 240 of 507 nephrologists (47.3%), The respondents were heavily i
nvolved in clinical dialysis work. Results showed that decisions regarding
modality selection were strongly based on patient preference (4.54 on a sca
le of 1 to 5), quality of life (4.18), morbidity (4.02), and mortality (3.9
0), whereas the least important factors reported were facility reimbursemen
t (2.09) and physician reimbursement (1.98). When asked about the current u
se of modalities, hospital-based HD and full-care HD were believed to be ov
erused (2.63 for each on a scale of 1 [vastly overused] to 5 [vastly underu
sed]), whereas home HD (4.29), continuous ambulatory PD (3.71), and cycler
PD (3.59) were underused. A hypothetical question about optimal modality di
stribution to maximize survival or cost-effectiveness showed that HD should
constitute 71% or 66% of dialysis (with 11% or 14% in the form of home HD,
respectively). PD use would increase between two- and threefold over curre
nt practices. Our results suggest that American nephrologists believe home
therapies are underused. Because modality distribution is an important dete
rminant of costs and possibly outcomes in patients with ESRD, there is an u
rgent need for further research in this area. (C) 2001 by the National Kidn
ey Foundation, Inc.