Background: Inadequate treatments are reported for depressed patients cared
for by primary care physicians (PCPs). Providing feedback and evidence-bas
ed treatment recommendations for depression to PCPs via electronic medical
record improves the quality of interventions.
Methods: Patients presenting to an urban academically affiliated primary ca
re practice were screened for major depression with the Primary Care Evalua
tion of Mental Disorders (PRIME-MD). During 20-month period, 212 patients m
et protocol-eligibility criteria and completed a baseline interview. They w
ere cared for by 16 board-certified internists, who were electronically inf
ormed of their patients' diagnoses, and randomized to 1 of 3 methods of exp
osure to guideline-based advice for treating depression (active, passive, a
nd usual care). Ensuing treatment patterns were assessed by medical chart r
eview and by patient self-report at baseline and 3 months.
Results: Median time for PCP response to the electronic message regarding t
he patient's depression diagnosis was 1 day (range, 1-95 days). Three days
after notification, 120 (65%) of 186 PCP responses indicated agreement with
the diagnosis, 24 (13%) indicated disagreement, and 42 (23%) indicated unc
ertainty. Primary care physicians who agreed with the diagnoses sooner were
more likely to make a medical chart notation of depression, begin antidepr
essant medication therapy, or refer to a mental health specialist (P<.001).
There were no differences in the agreement rate or treatments provided acr
oss guideline exposure conditions.
Conclusions: Electronic feedback of the diagnosis of major depression can a
ffect PCP initial management of the disorder. Further study is necessary to
determine whether this strategy, combined with delivery of treatment recom
mendations, can improve clinical outcomes in routine practice.